Doug Wilson answers by questioning the atheist's self-respect - what's it worth anyway if we're nothing but a bunch of 'churning chemical reactions.'
As the Day 1 exchange shows, among other things, the whole idea about God – even the possibility of his existence – is resisted by an atheist not because there is necessarily an absence of evidence (not that it doesn’t matter), but because if God does exist, there would be a massive reordering of lifestyle. For one, it would mean submission to a higher authority.
In the words of C.S Lewis, "Christianity, if false, is of no importance, and if true, is of infinite importance. The only thing it cannot be is moderately important."
That’s a discomforting thought, that someone should tell you how you should live in the "most intimate details of [your] life and mind." Better to be one’s own God, as it were.
Back to the Newsweek debate, there's quite a bit to chew, even if it was one-sided (also, the preamble was thick with the interviewer's own bias). I personally didn’t think Rick Warren was unnerved by the almost overbearing Harris. To Warren’s credit, I thought he conducted himself with appropriate humility. And even if Warren did not specifically address Harris’ objections, the appeal to Pascal’s Wager to my mind is no less a sensible apologetic.